Correlation of Post-Operative Outcomes in patients undergoing CABG Receiving Antegradecardioplegia alone Versus Combined Antegrade Plus Retrograde Cardioplegia: A Prospective Review

Aim: To compare the mean ejection fraction and cardiac enzymes level in patients with Ischemic heart disease undergoing elective coronary artery bypass graft surgery (CABG) having antegrade blood cardioplegia versus plus retrograde Cardioplegia. Study design: Randomized Controlled Trial Place duration: This study was performed from 7th February, 2020 to August, at Cardiac Surgery Department, PIC, Jail Road, Lahore. Methodology: After receiving informed consent, all CABG were enrolled this study. In order enzyme levels between who had those cardioplegia, preoperative, intraoperative, postoperative characteristics recorded into predesigned proforma. Results: The total number of 72 divided two groups. There 36(50%) have given Cardioplegia through route while According Table 1, age Group A 51.86±9.35 years, whereas ages participants B 52.92±7.70 years. 26(72%) male 10(28%) females 30(83%) 6(17%) B. BMI 25.65±5.18 25.02±3.97 35(97%) hypertensive 1(3%) non respectively. Similarly, there 33(92%) diabetic 3(8%) 28 (78%) 8(22%) smokers non- 24 (67%) 12(33%) non-smokers Practical Implication: comparison CKMB(IU/L) Antegrade group baseline after 48 hours shows insignificant p-values 0.17 0.12 respectively which that is no significant difference CKMB regarding these routes chosen for giving grafting. Conclusion: Although both required additional surgical manoeuvres, however, approaches equally effective safe. Prior research demonstrated multiple infusions offer superior protection either or alone. Keywords: Coronary Bypass grafting surgery, route, Retrograde Route, route.